PO-04-233 MULTIDISCIPLINARY APPROACHES TO TREAT VENTRICULAR ARRHYTHMIAS WITH RADIOABLATION AND CARDIAC SYMPATHECTOMY (MAVERICS)
نویسندگان
چکیده
Ventricular arrhythmias (VAs) are the most lethal arrhythmias. Established therapies to prevent occurrence of VAs include anti-arrhythmic drugs (AADs) and catheter ablation (CA). For patients with recurrent despite AADs CA, there exist novel treatment modalities such as cardiac sympathetic denervation (CSD) via percutaneous surgical approach stereotactic body radiation therapy (SBRT). The current study reports outcomes CSD SBRT from a tertiary care academic center. To report for refractory conventional CA. Study comprises all undergoing or at our center 10/2018 10/2021. Patients less than 2 months available follow-up data were excluded. Retrospective chart review was performed collate demographics, clinical characteristics, arrhythmia burden before after (maximum 12 months), complications during period. Burden in form episodes anti-tachycardia pacing (ATP) defibrillator shocks per month assessed primary efficacy outcome. Complications safety Overall, 25 underwent VAs. Thirteen excluded due insufficient follow up data. Of included patients, total 4, 5, 3 SBRT, CSD, both CSD/SBRT, respectively. Median age population 66 years (55-72). majority (10/12) male. left ventricular ejection fraction 30% (25%-34%). Eight had non-ischemic cardiomyopathy. number CA prior (2-5) 1 (0-2), Follow median (12-12) (9-12) intervention. 11 demonstrated reduction VA burden. Mean ATP shock significantly lower (39±43 vs 3±6; p= 0.008). No procedure-related observed Incorporation is associated reduced this single study. Further studies warranted validate these findings.
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2023
ISSN: ['1556-3871', '1547-5271']
DOI: https://doi.org/10.1016/j.hrthm.2023.03.1230